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Women who are pregnant, planning pregnancy, or breastfeeding should consult their obstetricians before considering glutathione therapy, and most healthcare providers recommend avoiding elective supplementation during these periods

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There is four decades of published research behind it

In a p48Cre/+-LSL-KrasG12D/+ mouse model, the proliferation of tumor cells was accompanied by a significant increase in ODC activity, and difluoromethylornithine (DMFO) treatment resulted in significant decreases in ODC, ARG1, spermine synthase (SMS), and spermidine synthase (SRM) expression and an increase in OAZ expression, which inhibited tumor progression [275, 276]

Understanding this distinction is important for patients experiencing digestive symptoms whilst taking B12 supplements